Tobacco-Control Efforts Prevented Nearly 800,000 Lung Cancer Deaths in the US Between 1975 and 2000March 28th 2012
Using detailed patient data and mathematical modeling programs, a US–international team of investigators has concluded that in the US, public health efforts beginning in the 1950s prevented nearly 800,000 deaths from lung cancer between 1975 and 2000.
Large Study of Female Cancer Survivors Highlights Poor Health BehaviorsFebruary 29th 2012
Following a large survey of more than 22,000 US women, researchers from H. Lee Moffitt Cancer Center, in Tampa, Florida, have concluded that a significant proportion of female cancer survivors have poor health behaviors, compared with women who have not had cancer.
Colonoscopy Beats Fecal Screening for Adenoma Detection in 50,000-Plus Patient COLONPREV StudyFebruary 29th 2012
Reporting interim findings from a multi-institutional assessment of more than 50,000 people 50 to 69 years of age, COLONPREV Study Group investigators from Spain have concluded colonoscopy is better than fecal immunochemical testing (FIT) at detecting adenomas.
Colonoscopic Polypectomy: Long-Term Benefit in Preventing Colon Cancer DeathsFebruary 28th 2012
A multi-institutional, NCI-funded retrospective study in the New England Journal of Medicine highlights the significant long-term benefit of colonoscopic polypectomy in preventing death from colon cancer, with polypectomy cutting the incidence of colon cancer–related mortality in half compared with the general population.
Racially Diverse Older Adults Continue to Be Screened for CancerDecember 19th 2011
A team of researchers from the University of Connecticut at Storrs and the National Cancer Institute, analyzing US national health data on more than 4,000 racially diverse adults aged 75 years and older, has concluded that despite “ambiguity of recommendations for this group,” cancer screening rates are high in this population.
Breast Density Reductions ID Preventive Benefit of TamoxifenDecember 19th 2011
Epidemiologist Jack Cuzick, PhD, and colleagues, writing in the Journal of the National Cancer Institute in April, concluded that “tamoxifen-induced reductions in breast density can be used to identify women who will benefit the most from prophylactic treatment with this drug.”
1-Day Canadian Program Impacts Oncology Nurse BurnoutDecember 19th 2011
Researchers from Wellspring, a Canadian nonprofit organization that supports and educates people with cancer, together with a team of patient-support consultants, have developed a 1-day program that appears to have reduced emotional exhaustion and burnout in oncology nurses.
CDC Program Offers Tools and Guidelines to Prevent Infections in Cancer PatientsNovember 22nd 2011
The often-weakened immune systems of cancer patients receiving chemotherapy put them at greater risk of acquiring life-threatening infections in community and hospital settings, including during appointments for outpatient treatment.
Persistence of PTSD Highlighted in Large NHL Survivor StudyNovember 22nd 2011
A survey of more than 500 long-term survivors of non-Hodgkin’s lymphoma (NHL) has revealed that more than one-third experience persistent or worsening symptoms of post-traumatic stress disorder (PTSD), with nearly 4 of 10 cancer survivors stating they still experience symptoms of PTSD more than a decade after their cancer diagnosis.
Small Increase in Diabetes Risk Seen in Older Breast Cancer Patients Taking TamoxifenNovember 22nd 2011
In a Canadian study of more than 14,000 breast cancer survivors over 65 years of age, current use of tamoxifen appears to be associated with a small increased risk of diabetes. The findings do not mean tamoxifen is a direct cause of diabetes in this patient population, the study authors emphasized, but they said its use may increase diabetes risk in older women who already have known risk factors for diabetes, such as obesity or a family history of the disease.
HE4 Biomarker Test Is Approved for Use in Risk of Ovarian Malignancy Algorithm (ROMA)October 19th 2011
In September 2011, the US Food and Drug Administration (FDA) approved marketing of the HE4 Test (Fujirebio Diagnostics, Malvern, Pennsylvania) along with the CA-125 test in the Risk of Ovarian Malignancy Algorithm, called ROMA, to determine the likelihood of finding malignancy at surgery in premenopausal or postmenopausal women presenting with an ovarian adnexal mass.
The Complexity of Hereditary Cancer SyndromesOctober 19th 2011
Counseling women at high risk for ovarian and uterine cancer is a complex process, from genetic diagnosisto the management of at-risk women. Rimes andcolleagues have presented these challenging issues, andsuggested ways to manage them, very well.
Vemurafenib, a BRAF Inhibitor for Patients With Unresectable or Metastatic Melanoma and V600E-Mutated BRAF ProteinOctober 19th 2011
Vemurafenib is a protein kinase inhibitor that blocks the mutated gene protein BRAFV600E so that the cascade of messages that drive cell division and prevent apoptosis is stopped, resulting in tumor shrinkage.
Coenzyme Q10, or CoQ10, is a naturally occurring, lipid-soluble antioxidant and an essential electron carrier involved in the mitochondrial respiratory chain. In mitochondria, CoQ10 functions as a coenzyme that assists in the oxidative phosphorylation of nutrients, leading to production of cellular adenosine triphosphate (ATP), or energy.
October Is National Breast Cancer Awareness MonthOctober 19th 2011
The National Breast Cancer Awareness Month (NBCAM) organization, which began its campaign in 1984, is a partnership of more than a dozen national professional medical associations, public service organizations, and government agencies that work together year-round to promote awareness of breast cancer, share up-to-date information about the disease, and provide greater access to screening services.
EMCC: AZURE Subgroup Analysis Shows Adjuvant Therapy With Zoledronic Acid May Benefit Breast Cancer Patients Postmenopausal > 5 YearsSeptember 29th 2011
Results of the AZURE trial revealed small improvements in disease-free and overall survival when zoledronic acid was used in addition to adjuvant therapy in a subgroup of early-stage breast cancer patients who had been postmenopausal for more than 5 years.
Nurse Practitioners and Physicians' Assistants May Play Critical Roles in Future of Oncology CareSeptember 23rd 2011
A new study of collaborative oncology practice models showed that the greater use of nonphysician practitioners (NPPs) led to an increase in productivity for the practice and was satisfying for both physicians and the NPPs. This provides one potential solution for the predicted shortage of oncologists in the next decade.
High Skin, Eye Exposure to Chemo in Ambulatory Care Nurses Underscores Need to Shore Up Safety PracticesAugust 30th 2011
A statewide survey of oncology nurses administering ambulatory chemotherapy found a high rate of self-reported chemotherapy exposure, with nearly one-fifth of nurses surveyed experiencing skin and eye exposure in the last year.
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